Abstract

In menopause, changes in body fat distribution led to increasing risk of cardiovascular and metabolic diseases. Therefore, the prediction of cardiovascular disease (CVD) by the presence of risk factors is of importance in elderly women. Materials and Methods: The study was conducted among 120 rural young, middle-aged and elderly women, selected randomly outpatient at Department of Obstetrics and Gynaecology, Mamata Medical College, Khammam. Components of metabolic syndrome (MS), body fat percentage, different lipid profile fractions and body mass index (BMI) were measured. Statistical tests were calculated using SPSS software version 20.0. p≤0.05 was considered statistically significant. Results: Postmenopausal women (50±5 years) were older than premenopausal women (35±5 years) and BMI did not differ between the two groups. After adjustment for age and BMI in total and non-obese subjects (not obese subjects), postmenopausal women exhibited higher haemoglobin A1c and total cholesterol levels than premenopausal women. Subgroup analysis for 60 postmenopausal and 60 age- and BMI-matched premenopausal women showed that postmenopausal women had higher total cholesterol levels than premenopausal women with marginal significance. Conclusion: High prevalence of metabolic syndrome existed among elderly women. Significant correlation existed between menopause and different CVD risk factors as well as some of the components of MS indicating a possible coexistence of different CVD risks.

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