ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    Is platelet rich plasma enriched bone graft superior to bone graft alone in lumbar interbody fusion


    Dr. Mohammed Akram Uddin, Dr. Kishore Reddy A, Dr. Kodide Umamaheswar
    JCDR. 2023: 272-281

    Abstract

    To study Radiological Union in Lumbar Interbody Fusion treated with Platelet Rich Plasma & Bone Graft and Bone Graft Alone. Methodology: This is a Prospective Randomized study in Department of Orthopaedics, Kamineni Institute of Medical Sciences, Narketpally during October 2019 to September 2021.The aim of this study is to evaluate the Radiological Union in Lumbar Interbody Fusion treated with Platelet Rich Plasma & Bone Graft and Bone Graft Alone. 24 patients with 12 patients in each group, Group-A (ABG+PRP) & Group-B (ABG Alone) with single level lumbar Spondylolisthesis were treated with Posterior Lumbar Interbody Fusion with Platelet Rich Plasma and Autologous Bone Graft & Autologous Bone Graft Alone. Results: In the present study, PRP is a Platelet Rich Plasma with high concentration of platelets used as osteoinductive with AGFs. Radiological outcome was significant in PRP group than in control group at 6months. Whereas on long term follow-up there is no significant difference in bone fusion between the PRP group and Control group. Conclusion: This study suggests that the use of Platelet Rich Plasma along with Autologous Bone Graft promotes faster bone fusion and decreases the average duration of bone union in short term follow-up

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    Volume & Issue

    Volume 14 Issue 10

    Keywords