ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    Ketamine and dexmedetomidine for prevention of pain due to Propofol injection


    Dr. Swarna Rekha R.V
    JCDR. 2022: 758-761

    Abstract

    Patients frequently report experiencing excruciating discomfort upon receiving an injection of propofol, which is understandable given the nature of the situation. Propofol, on the other hand, is a well-liked intravenous anaesthetic induction agent. It allows for a smooth and speedy induction, as well as a speedy clearance and recovery. Inducing substances like ketamine, which is a derivative of the drug phencyclidine, and dexmedetomidine hydrochloride, which is an imidazole molecule, are both examples of the class of drugs known as alpha 2 agonists. Ketamine is a derivative of phencyclidine, while dexmedetomidine hydrochloride is an imidazole molecule. In the present study, a comparison was done between the efficacy of ketamine (0.5 mg/kg) and dexmedetomidine (0.5 mcg/kg) in reducing the intensity of the pain generated by propofol injection and preventing its occurrence. Both medications were given. The dose of ketamine that was administered was 0.5 mg/kg and the dose of dexmedetomidine that was administered was 0.5 mcg/kg.

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    Volume & Issue

    Volume 13 Issue 6

    Keywords

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