Abstract

LV diastolic dysfunction contributes to signs and symptoms of heart failure and LV diastolic dysfunction is associated with increased mortality rates in patients chronic heart failure independent of systolic function after acute myocardial infarction. This study was planned to calculate the mean change in LV diastolic function at 3 months and 1 year after MI from baseline. Materials and Methods: This hospital-based retrospective observational study was carried out in a tertiary care facility at Jaipur. Data of total 75 patients of acute MI who got admitted from 1st April 2022 to 30th September 2022 was collected retrospectively. Baseline and follow up data of clinical evaluation of all patients visits at 3 and 12 months along with Two-Dimensional Echocardiography for assessment of Diastolic Dysfunction was obtained from the records and analysed. Result: The mean age of cases was 63±11 years. Male to female ratio was 2.9:1. Patients with normal, impaired relaxation, or restrictive LV diastolic Doppler filling were categorized in 38.7%, 40%, and 21.3% respectively. In patients with normal filling pattern early and late mitral peak flow velocity, E/A ratio, and mitral E-wave deceleration time were without significant changes during 12 months of follow-up. In patients with impaired relaxation E/A ratio, mitral E deceleration time, isovolumetric relaxation time, and peak pulmonary venous systolic and diastolic flow velocity were unchanged during follow-up. Conclusion: Patients exhibiting early diastolic dysfunction symptoms develop LV dilatation and in-hospital congestive heart failure. Patients who developed this LV filling abnormality or who had a prolonged restrictive LV filling pattern were linked to higher NYHA class scores and hospital readmissions for heart failure during follow-up.

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