Abstract

Chronic kidney disease (CKD) is an important cause of morbidity and mortality worldwide. Progressive renal failure is associated with characteristic alterations in lipoprotein metabolism and dyslipidemia. Heart disease is also a major cause of mortality and morbidity among patients with renal failure. Materials and Methods: A hospital based cross sectional study was conducted in Imphal among 572 CKD patients admitted during January 2018 to December 2022. The lipid profile was measured and echocardiography was performed for all the participants. Data was analysed using SPSS version 21 software and reported as frequencies and percentages. Results: 40% of the patients had triglycerides ≥ 200 mg/dl, while LDL ≥160 mg/dl and cholesterol ≥240 mg/dl was found in 10% of the patients. HDL was <40 mg/dl in 54% of the patients. Left ventricular hypertrophy (LVH) was found in 96% of the patients; LVD, PE and LVDD were found in 38%, 34% and 32% of the patients respectively. Conclusion: Dyslipidemia and echocardiographic changes are common in CKD patients with four out of every 10 CKD patients having high levels of triglycerides and majority having left ventricular hypertrophy.

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