Journal of Cardiovascular Disease Research
Liver stiffness quantification in patients with fatty liver using shear wave (2d) elastography
Dr. Kashish Mahajan, Dr. Anchal Gupta, Dr. Ishween Kour, Dr. Roopali Mangotra, Dr. Kulbhushan Gupta
JCDR. 2023: 1394-1400
Abstract
Inflammation & stiffness of the hepatic tissue, which leads to cirrhosis, portal hypertension, & ultimately hepatocellular cancer, is the main effect of fatty liver disease. Elastography & the fibrosis score have been investigated as non-invasive objective replacements for biopsy & other methods to reduce reliance on them. The aim of current study was to quantify liver fibrosis by using shear wave elastography in patients with fatty liver & also to determine the degree of stiffness & therefore the stage of liver fibrosis. Material & methods: This hospital based prospective study was conducted Department of Radiodiagnosis, Govt. Superspeciality hospital, GMC Jammu during a period of 6 months. Total 50 participants underwent underwent 2D shear wave elastography & the values were compared with metavir scores. Statistical analysis was performed using Statistical Package for the Social Sciences (SPSS) statistics version 23.0. Results: The mean age was 46.8±10.9 years including 26% females and 74 % males. The maximum (60%) subjects had fatty liver grade 1 and 4% had cirrhosis. The 44% subjects had metavir score of F0. The average SWE score of subjects was 7.14 ± 5.04 kPa. Conclusion: Shear wave elastography in two dimensions performed well in terms of diagnosing liver stiffness.
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