Journal of Cardiovascular Disease Research
LUNG INVOLVEMENT IN PARAQUAT POISONING: UNRAVELLING THE COMPLEX WEB
Pataballa Shanmukha Satya Sai Krishna, P. Maneesha, V. V. S Suresh, M. Venu
JCDR. 2024: 1386-1392
Abstract
Paraquat, a widely used herbicide known for its efficacy in weed control, has gained notoriety for its potential toxicity to humans. The current study examines the manifestations, consequences, and course of paraquat intoxication. Methodology: At our tertiary care center, 10 cases of paraquat poisoning were recorded during the course of the study, which lasted a full year. In our study, all cases included purposeful ingestion, meaning the patient attempted suicide. Out of ten patients, only one patient survived. This suggests that patients who present early (4 hours) and with less ingestion have a higher chance of surviving. Conclusion:Among the various systemic effects associated with paraquat poisoning, lung involvement stands out as a critical and often fatal manifestation. According to our study, pulmonary fibrosis, Respiratory failure and ultimately multi-organ failure are the most frequent consequences that result in mortality. This article explores the intricacies of lung complications arising from paraquat exposure, shedding light on the underlying mechanisms, clinical presentation, diagnostic challenges, and potential therapeutic interventions.
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