Abstract

The purpose of this study was to assess the diagnostic value of CT enterography using mannitol as a negative contrast agent for the demonstration and diagnosis of bowel diseases in correlation with the histological diagnosis. Methods: Its a prospective cross-sectional observational study was carried out among 60 patients with suspected bowel pathologies in the Department of Radiology at the Mysore Medical College and Research Institute, attached to K. R. Hospital, Mysore, over the course of 18 months, from January 2021 to June 2022, After getting approval from the institutional ethics committee and signed informed consent from the study participants, Results: Of the 60 patients studied, 35 were males and 25 were females, with a slight male predominance. Most of the patients with benign lesions were in the age group of 30-39 years and those with malignant lesions were in the age group of 50-59 years. Most of the patients had bowel distension grade 3 (>80%) and grade 2 (50- 80%), suggesting bowel distension was excellent in most of the patients. Sensitivity, specificity, positive predictive value and negative predictive value of CTE in the diagnosis of benign intestinal diseases were 97%, 93%, 97%, and 93% respectively and sensitivity, specificity, positive predictive value and negative predictive value of CTE in the diagnosis of malignant intestinal diseases were 93%, 97%, 93% and 97% respectively. Conclusion: In routine practice, CT enterography is an acceptable and applicable modality for the diagnosis and differentiation of intestinal pathologies, as well as for differentiating benign from malignant lesions. The taste of mannitol is good, acceptable, and tolerable, all of which helped in achieving adequate luminal distension and a good quality of image with the fewest artefacts.

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