Abstract

Coronary Artery Disease (CAD) is one of the leading causes of mortality in both developed and developing countries. One of the major culprits among the risk factors of CAD is Metabolic Syndrome (MS). Many clinical studies have been done on the association between MS and increased risk of CAD. The prognostic importance of MS compared to the individual components has been repeatedly challenged. This study addresses the issue of objectively assessing the severity of CAD by using standard scores and tools among patients with MS over their counterparts. Methodology: This is a period based observational study. 100 patients (half having MS while the other half without MS), who were referred coronary artery angiography due to suspected CAD were selected for the study. Every patient was inquired in detail about the case history. The syntax score system is used to show the severity of CAD. Results: Patients with MS are more prone to CAD compared to patients without MS. In patients with MS- 4% of study participants are having high syntax scores, 72% of study participants are having intermediate syntax score, 24% of study participants are having low syntax score. There is no significant difference P (0.714) in relation to gender and syntax score in developing CAD. Results suggested that elevated waist circumference, reduced HDL-C, and elevated fasting glucose might have the relatively higher association with CAD and MS, whereas elevated TGs and high blood pressure might have weaker association. Conclusions: This study helped us to understand the severity of disease in patients with MS and compare with their counterparts. It gives the information that MS is in significant relation with the syntax score and CAD P (0.000). So, angiographic severity of CAD among MS is higher than the counterpart.

Description