Abstract

Liver abscess is a well-known condition that is often caused by parasite origin (amoebic) in underdeveloped nations and pyogenic in affluent ones. The goal of this research was to assess the microbiological spectrum of liver abscess, its etiological reasons, the medication susceptibility pattern of the isolates from the liver abscess, and the illness outcome. Materials and Procedures: From January 2021 to June 2022, prospective cross-sectional research was done at the Department of Microbiology on 90 patients diagnosed with a liver abscess in the Department of Surgery of a tertiary care hospital. Results: The most common etiological aetiology of the liver abscess (71%) was amoebic liver abscess. The most prevalent causal organism of pyogenic liver abscess (11%) was E. coli. The bulk of the patients were middle-aged guys with low socioeconomic position and were chronic drinkers. Fever (89%) and stomach discomfort (62%) were the most prevalent symptoms, with hepatomegaly (58%) being a common indicator. The research found complications such as abscess rupture (four instances), sepsis (four cases), chronic liver disease (two cases), and liver failure (two cases). The treatment approach in this research includes beginning patients on a first empirical antibiotic regimen. In addition, in the majority of instances, abscess drainage was performed using fine-needle aspiration (42%), or pigtail drainage (27%). Only 11% of the cases were complex enough to need open surgery. Conclusion: Amoebic liver abscess is the most frequent kind of liver abscess in India, followed by pyogenic liver abscess. The most prevalent bacterium recovered from pyogenic abscesses is E.coli. The most prevalent pattern in our investigation was a solitary right lobe abscess. Early and adequate antibiotic therapy, as well as abscess drainage, have resulted in a better clinical outcome.

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