Abstract

Background- HF according to recent definition is described as a clinical illness characterized by signs and/or symptoms brought on by a structural or functional cardiac defect, which was supported by objective evidence of systemic or pulmonary congestion or by high levels of natriuretic peptide. We aimed to assess the role of N Terminal-Pro Brain Natriuretic Peptide (Nt Pro BNP) levels in Congestive Cardiac Failure and controls as well as to assess its correlation with age, gender, body mass index, troponin, electrocardiographic and 2D echocardiographic abnormalities in patients with CCF. Methodology- This study was conducted as a case control study on patients with Congestive Cardiac Failure according to Framingham criteria presenting at tertiary care hospital during the study period of 18 months i.e. 01/06/2022 to 30/11/2023 in central India. A total of 100 cases with HF and 30 controls were included and were subjected to detailed history, clinical examination and routine and special investigations like NT pro BNP. Results- NT Pro BNP was found to be raised (>400 ng/ml) in 96% cases and 10% controls and the observed difference was statistically significant (p<0.05). Our study found no significant association of NT ProBNP with age, gender, BMI as well as Troponin I (p>0.5), however, ECG as well as echocardiographic abnormalities correlated with NT Pro BNP significantly (p<0.05).

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