Abstract

Primary angle-closure glaucoma is one of the significant causes of blindness worldwide. It is a disease related to ocular anatomy that is related to pupillary-block and angle-crowding. Eyes prone to primary angle-closure are small with decreased AXL, ACD, and filtration angle width, associated with a proportionately large lens. As the age progresses, there is a decrease in anterior chamber depth because of increasing lens thickness. Aim: The purpose of this study is to compare the differences in Ocular Biometric measurements among different stages of PACG, including 1) Primary angle-closure suspect, 2) Primary angle closure, and 3) Primary angle-closure glaucoma. Methodology: A study titled "Ocular Biometry in Different Stages of Primary Angle Closure Glaucoma" was undertaken at the regional eye hospital, Kurnool, from November 2018 to October 2020. In the present study, 111 eyes were included after fulfilling the inclusion criteria. Results: In the total of 111 eyes, 29 eyes of open angles(control group),40 eyes of PACS,12 eyes of PAC, and 30 eyes with PACG with a clear lens were subjected to ocular Biometric parameters like ACD, LT, AXL, LAF, RLP, CD, Mean keratometry. After completing the study, the results were analyzed. In the PACS group - The mean axial length was 22.17±0.27, Mean LT was 4.54±0.25, Mean ACD was 2.38±0.15, mean LAF was 2.04±0.11, Mean RLP was 2.1±0.07, Mean CD was 11.25±0.06, Mean keratometry was 45.63±0.19. In PAC Group - Mean axial length was 22.34+0.11, Mean LT was 4.38±0.16, Mean ACD was 2.38±0.14, mean LAF was 1.96±0.07, Mean RLP was 2.05±0.08 Mean CD was 11.4±0.05, Mean keratometry was 45.38±0.38. This study revealed a thicker lens(p=0.001) and showed a significantly anteriorly placed lens(p<0.001) compared to the controls and thus is an essential contributing factor in producing a shallower chamber. The AXL in the present study was considerably less in PACS and lesser in PACG in the eyes. The lens was detected to be anteriorly placed (p<0.001) in PACG, PAC, and PACS compared to open angles. The corneal diameter(p<0.001) is shorter in PACG, PAC, and PACS compared control group. The Corneal Curvature (Mean Keratometry) (P=0.001) is steeper in PACG, PAC, and PACS than open angles. Conclusion: In this study, PACS eyes were associated with short axial length, shallow anterior chamber, thick crystalline lens, anteriorly placed lens, small corneal diameter, and steep corneal curvature than the eyes of the open-angle group. PAC eyes were associated with shallow anterior chambers, thick crystalline lens, anteriorly placed lens, small corneal diameter, steep corneal curvature compared to the open-angle group.

Description