Abstract

Background: Pancytopenia is a hematological condition which occurs commonly and etiology varies according to different geographic location. Finding out specific etiology is important for appropriate management. Aims and Objectives: The present study was undertaken to describe etiological factors which leads to pancytopenia in “Central Clinical Laboratory (CCL), Department of Pathology, P.D.U Medical College & Hospital, Rajkot”. Materials and Methods: A prospective study was conducted for a period of six months between September 2023 to February 2024 in which 220 patients were included. After acquiring clinical history, complete blood count including peripheral smears was done. Afterward, bone marrow aspiration was performed and microscopically examined in selected cases. Results: Among 220 patients studied, 134(60.09%) were males and 86 (39.09%) were females. Mean age was 38 years. The most common cause of pancytopenia was found to be megaloblastic anemia in 68 patients (30.90%) followed by thalassemia in 26 patients (11%). Other common causes included alcoholic liver disease in 20 patients (9.10%) and acute myeloid leukemia in 16 patients (7.27%), severe sepsis in 16 patients (7.27%).

Description