ISSN 0975-3583
 

Journal of Cardiovascular Disease Research

2021, Vol: 8, Issue: 8
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    Pathophysiology of psoriasis and the roles of nucleolar phosphoprotein-1 (NPM1) and glucose dependent insulinotropic polypeptide 3 (G1P-3)


    Dr Subodh Kumar, Dr Pooja Nupur, Dr Naveen Kumar , Dr Ramawatar Singh
    JCDR. 2024: 2024-2030

    Abstract

    Background: Psoriasis is a prevalent chronic systemic inflammatory disease affecting over 2% of the global population, characterized by skin and systemic manifestations. Recent research has highlighted the role of non-coding RNAs, such as PRINS and the gene Interferon Alpha Inducible Protein 6 (IFI6 or G1P-3), in the disease's pathogenesis. These molecules, particularly in response to stress, may influence psoriasis susceptibility and severity. This study investigates the levels of G1P-3 and nucleolar phosphoprotein (NPM) in serum and tissue samples from psoriasis patients compared to healthy controls to assess their roles in psoriasis development.

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    Volume 15 Issue 5

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