Abstract

The magnitude of pain experienced with major surgical procedures such as complete knee replacement is substantial. This study aims to evaluate the effectiveness of periarticular injection of a combination of analgesic medicines in reducing pain following total knee replacement surgery. Material and Methods: This investigation was conducted using a randomized controlled trial design. The study encompassed a cohort of 20 patients. The research investigation was carried out at the Department of Orthopedics, Kakatiya Medical College / MGM hospital, located in Warangal, Telangana, India, throughout the period spanning from March 2022 to February 2023. The orthopaedic outpatient department assessed both cases and controls, providing a comprehensive explanation of the study and distributing an information sheet for further clarification. Results: The pericapsular injection of medicines resulted in much superior pain alleviation for patients in the early postoperative period, as compared to the epidural group. The pericapsular injection resulted in a more rapid functional rehabilitation in the patients. However, on the 10th day after the operation, there was no significant difference observed in terms of functional ability or pain relief. The modality of pain control did not have a substantial impact on the range of motion. Individuals who were administered pericapsular injections experienced a reduced incidence of anaesthesia-related adverse effects, such as nausea, pruritis, vomiting, and urine retention. Conclusion: Patients who got peri capsular injection experienced considerably superior pain relief on the day of surgery compared to those who received epidural injection for postoperative pain reduction

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