Abstract
Sheehan's Syndrome, characterized by hypopituitarism resulting from postpartum pituitary necrosis, can present with a myriad of symptoms, making diagnosis challenging [1,2,3]. We present a case of a 34-year-old female with a history of postpartum hemorrhage who presented with symptoms of fatigue, dyspnea, and pericardial effusion on 2D echocardiography. Despite multiple clinic visits over three years, the diagnosis remained elusive until extensive evaluation revealed central hypothyroidism, low cortisol, FSH, LH, and prolactin levels. MRI confirmed partial empty sella, consistent with Sheehan's Syndrome. Hormonal replacement therapy led to significant clinical improvement, highlighting the importance of early recognition and appropriate management [4,5,6,7,8].