Abstract

The aim of our study was to study the clinical and sleep profile in patients with Metabolic Syndrome and sleep disturbances by polysomnography. We also studied the association of Metabolic Syndrome and Obstructive Sleep Apnea Syndrome. Materials & Methods: This is a prospective observational study conducted on 76 patients of metabolic syndrome. National Cholesterol Education Program - ATP III protocol was used for the diagnosis of metabolic syndrome. All the patients fulfilling the inclusion criteria were subjected to whole night polysomnography. We compared the sleep related complaints and individual risk factors of metabolic syndrome with Apnea-Hypoapnea Index (AHI). We also did a subgroup analysis by age, sex, sleep complaints and sleep profile. Results: In our study we found a significant correlation on comparison of hypertension to the AHI of the patients and no correlation between diabetes mellitus and AHI. It was also seen that deranged lipid profile leads to higher AHI. Abdominal circumference and BMI were cross tabulated with AHI and significant correlation was seen. When the patients of metabolic syndrome were subdivided by the number of risk factors they fulfil, it was found that as the number of risk factors increases, the chances of higher AHI scores also increases. Conclusion: The close relation between metabolic syndrome and OSAS may be due to the common mechanistic links between the two. All the patients with metabolic syndrome should be considered as potential risk for developing OSAS and should be evaluated extensively including polysomnography.

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