Abstract

This study was aimed to assess the prevalence and clinical profile of MetS among type-II DM patients attending a tertiary care centre. Methodology: A hospital based cross sectional study was conducted at Department of Medicine of a tertiary care centre. The aim of the study was to find the prevalence and association of metabolic syndrome and its components in Type 2 Diabetes Mellitus cases. Study included 200 known or newly diagnosed type 2 diabetic patients coming at our hospital. Following observations were made during the study: Results: Most of the diabetics patients belong to age group of 51 to 70 years (64.5%) with mean age of cases as 55.9 years. Out of total 200 diabetic patients, 54% were males and 46% were females. Newly diagnosed diabetics were 7.5% while 92.5% were known cases of diabetes Mean duration of diabetes among cases was 8.13 years with one third (32%) cases having known diabetics for over 10 years. Prevalence of metabolic syndrome among diabetics was observed as 58%. Prevalence of metabolic syndrome was 62% among males and 53.3% among females. The difference was statistically non-significant (p-0.41). Mean age of diabetic cases with MS was significantly higher as compared to cases without MS (58.78 vs 51.96 years; p<0.01). Mean duration of diabetic in cases with MS was significantly higher as compared to cases without MS (10.34 vs 5.01 years; p<0.01). Prevalence of metabolic syndrome was 60.5% among old cases while it was 26.7% among newly diagnosed diabetics (p<0.01). Prevalence of MS in newly diagnosed cases was 26.7%, which increases with increase in duration of diabetes as follow: 35.0% in duration of 1 to 5 years, 60.5% in duration of 6-10 years and 90.6% in duration > 10 years (p<0.01). Among parameters of metabolic syndrome, raise blood pressure was seen in 52% cases, high waist circumference was seen in 13% while low HDL and high TGs was seen in 28.5% and 51% cases respectively. A significant association between derangement of MS parameters was observed with duration of diabetes (p<0.01). Conclusion: Our study demonstrates that metabolic syndrome is extremely common among diabetic patients. Metabolic syndrome affects every three out of five known diabetics and found in every one out of three newly diagnosed cases. Increasing prevalence was observed to be associated with increasing duration of diabetes.

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