Abstract

COVID-associated mucormycosis (CAM) is an emerging complication in COVID-19 patients. These patients undergoing surgery may face high anesthesia-related risks. We aimed to determine the prevalence and risk factors for perioperative anaesthesia complications in CAM patients undergoing surgery. Objectives: This study was carried out to determine the prevalence of perioperative anaesthesia complications in CAM patients undergoing surgery and identify associated risk factors. Materials & Methods: We retrospectively analyzed 715 CAM patients who underwent surgery at a tertiary hospital in India from April 2021 to July 2021. In this study, the type of mucormycosis, comorbidities, perioperative anesthesia complications, airway management issues, and mortality were recorded and analyzed. Result: The overall anaesthesia complication rate was 51.89%. The most frequent complications were hypertension (21.53%), difficult airway (16.91%), requirement of postoperative respiratory support (13.14%), noninvasive ventilation (6.57%), reintubation (4.47%), hypotension (10.06%), and delayed recovery (9.23%). Rhinosinusitis (51.05%) and rhino-orbital mucormycosis (21.54%) predominated. Major comorbidities were diabetes (66.85%), cardiac involvement (72.73%), and chronic respiratory disease (58.74%). Increasing age, high ASA status, extensive infections, diabetes, and respiratory illness predicted complications. Mask ventilation was difficult in 17.76% and intubation in 10.91% of patients. Mortality was 5.45% within 24 hours and 12.73% by 72 hours postoperatively. Conclusion: Perioperative anesthesia complications are common in CAM surgery patients, especially those with comorbidities and extensive disease. Individualized management plans are essential to optimize airway, respiratory, hemodynamic, and metabolic parameters for mitigating morbidity and mortality

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