Journal of Cardiovascular Disease Research
Prevalence and Risk Factors of Ventilator-Associated Pneumonia in Pediatric Intensive Care Units: A Cross-Sectional Study
Dr Nikhil Pathak, DR Lalit Une
JCDR. 2023: 837-843
Abstract
Ventilator-associated pneumonia (VAP) is a critical concern in pediatric intensive care units (PICUs), significantly impacting the health of critically ill children. Understanding the prevalence and risk factors associated with VAP is paramount for improving patient care and outcomes in this vulnerable population. Objective: This cross-sectional study, conducted over a [duration] period in [location], aimed to investigate the prevalence of VAP and identify its risk factors among pediatric patients admitted to PICUs. Methods: Data from 150 pediatric patients admitted to 5 PICUs were analyzed. Inclusion criteria encompassed patients aged 1 month to 18 years who required mechanical ventilation during their hospitalization, ensuring a representative sample of the PICU population. Patient demographics, clinical variables, and laboratory data were collected. Statistical analysis, including logistic regression, was employed to identify independent risk factors associated with VAP. Results: The study revealed a VAP prevalence of 14.2% among the study cohort. Several significant risk factors were identified, including prolonged duration of mechanical ventilation, longer lengths of PICU stay, and prior antibiotic usage. Notably, patients with durations of mechanical ventilation exceeding 7 days had a significantly higher risk of developing VAP (OR=2.45, p<0.001). Statistical analysis demonstrated robust associations, with odds ratios and p-values confirming the statistical significance of these factors. Conclusion: This cross-sectional study, involving 150 pediatric patients in PICUs, illuminates the prevalence and risk factors associated with VAP. The findings serve as a valuable foundation for developing evidence-based strategies aimed at reducing VAP incidence and improving the overall well-being of critically ill pediatric patients.
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