Abstract

MRSA is one of the most important pathogen implicated in minor skin and soft tissue infections including abscess, cellulitis, necrotizing fasciitis to chronic bone infections and post-surgical wound infections. The magnitude of Staphylococcus infection and emergence of its antibiotic resistant has increased day by day due to irresponsible and over use of antibiotics, contamination during operative procedures, prolong stay in hospital, lack of antisepsis measures etc. Methods: 200 S.aureus isolated from pus samples of patients who attended in OPD and admitted in IPD during 2019-2020. S.aureus was isolated from pus samples which were identified by direct microscopy, biochemical tests and antibiotic susceptibility testing and Methicillin resistance was detected by disc diffusion tests according to CLSI guidelines. Results: Out of 200 Staphylococcus aureus isolated from pus samples, the rate of incidence of S.aureus was 60.5% in males and 39.5% in female and predominance of MRSA isolates was 51% and MSSA isolates was 49%. Abscesses was most prevalent in MRSA isolates. The incidence of postoperative wounds was high in male than female. Vancomycin and linezolid were most effective drugs against Staphylococcus aureus isolates with 100% sensitivity. Ampicillin and Ciprofloxacin were the least effective drugs against MRSA. Conclusion: Periodic surveillance on rate of postoperative wound and its associated factors, infection control, patient management and antimicrobial susceptibility should be done. Patient isolation and strict enforcement of hand washing should be done to prevent colonization and infection in order to deduce the spread of MRSA infection.

Description

.