Abstract

Background: Stroke is characterized by the sudden onset of neurological deficits lasting more than 24 hours due to a focal vascular cause. Stroke patients often exhibit hyperglycemia and dyslipidemia, with elevated levels of C-reactive protein (CRP) associated with an increased risk of ischemic stroke. Understanding the glycemic status, lipid profile, and CRP levels in stroke patients is crucial for effective management and prevention. Objective: This study aimed to assess the glycemic status, lipid profile, and CRP levels in stroke patients admitted to a teaching institute in northeast India. Methods: A cross-sectional hospital-based study was conducted at the Department of General Medicine Great Eastern Medical School and Hospital Ragolu,Srikaulam.Data analysis was performed using SPSS software version 15, employing appropriate statistical tests. Results: Among the 150 stroke patients included in the study, 55% were found to be prediabetic, 35% were known diabetics, and 10% were newly diagnosed diabetics. Additionally, 60% of patients had hypertension. Ischemic stroke was predominant (75%) compared to hemorrhagic stroke (25%). Hypercholesterolemia was observed in 70% of patients, while 65% had hypertriglyceridemia. Moreover, 75% exhibited raised serum LDL levels, and 60% had decreased serum HDL levels. Notably, 65% of the patients had elevated serum CRP levels, with 60% of ischemic stroke patients and 5% of hemorrhagic stroke patients showing elevated CRP levels. Conclusions: Prediabetes and newly diagnosed diabetes are prevalent in stroke or TIA patients, emphasizing the need for early detection and intervention. Considering the escalating prevalence of prediabetes, targeting it for primary and secondary prevention could be paramount. Additionally, early identification of dyslipidemia and its management, including drug therapy, dietary modifications, and lifestyle changes, could mitigate stroke risk. However, the cross-sectional nature of this study warrants further validation through long-term prospective studies.

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