Abstract

The range of microorganisms that can result in newborn sepsis shifts throughout time and differs from one geographic location to the next. It is also possible for there to be differences from one hospital to another within the same city. This is because of shifts in the way antibiotics are used as well as alterations in people's lifestyles. In the 1960s, the most common cause of newborn sepsis in both Europe and the United States was caused by Gram-negative germs. In the newborn intensive care unit of our hospital, which is a tertiary care centre, a prospective hospital-based study was conducted over the course of one year. The study lasted for 365 days. At least twenty percent of deliveries necessitate admission to the nursery. Sepsis testing was performed on all newborns who were either delivered in the hospital and had signs and symptoms of sepsis or were delivered to moms who possessed possible risk factors for sepsis. As research cases, we included all of the neonates who had a diagnosis of culture-positive sepsis or clinical sepsis with multidrug-resistant pathogens. The CONS organism was the most prevalent, accounting for 32.79 percent of all cases, followed by Klebsiella species (16.39 percent) and Staph aureus (14.7 percent). One hundred percent of the CONS positive cultures did not have MDR. Whereas multidrug-resistant Klebsiella and staphylococcal strains were found in 70% and 100% of Staph species respectively.

Description