Abstract

The purpose of this research was to assess the factors linked with the severity of acute pancreatitis. Methods: For one-year, prospective observational research was conducted at the Department of General Surgery at SCB Medical college and hospital, Cuttack. This research comprised 80 patients who were diagnosed with acute pancreatitis based on clinical indications, biochemical markers, and radiological findings. Various blood tests were performed on them, including haemoglobin, total leukocyte count, differential count, haematocrit, calcium, Blood urea nitrogen (BUN), arterial blood gas analysis, serum electrolytes, Random blood sugar (RBS), liver function tests, Lactate dehydrogenase (LDH), serum amylase, serum lipase, ultrasound abdomen, and contrast. CT scans for individuals who are suggested. The two most often used scoring methods at our university, Ranson's score and modified Glasgow score, were also examined. RESULTS Most instances (37.5%) were observed in people aged 40 to 50. In our research, 56 patients (70% of the total) had mild acute pancreatitis, 15 had moderately severe acute pancreatitis (18.5%), and 9 had severe acute pancreatitis (11.25%). Most patients with acute pancreatitis in our research, 56 (70%), were caused by alcohol. 14 (17.5%) of the cases were due to gallstone pancreatitis. In our research, 50 patients (62.5%) had diabetes, 32 (40%) had hypertension, and 40 (50%) had dyslipidaemia. Diabetes mellitus was the most common co-morbidity in the study population. In our analysis, 38 instances (47.5%) had a BMI between 18.5 to 24.9, 8 (10%) had a BMI more than 30, and 34 (42.5%) had a BMI between 18.5 and 19.9. The majority of the 56 instances (70%) who presented had a drinking habit. In our research, 4 (5%) individuals died as a result of severe acute pancreatitis complications. The mean BMI for those with mild acute pancreatitis was 25.470.21 (standard error (SE)), 29.540.62 for those with moderately severe acute pancreatitis, and 29.871.67 for those with severe acute pancreatitis. Conclusion: For successful therapy, one should not rely on a single grading system. Pancreatitis should be diagnosed clinically, laboratory, and radiologically, and vigorous crystalloid resuscitation with intensive care monitoring should begin as soon as possible.

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