Abstract

Cholecystitis is one of the commonest biliary pathologies defined as chemical or bacterial inflammation of the gallbladder. Although it occurs in a variety of pathological and clinical forms, cholecystitis associated with gallstones is the most common type, occurring in about 90-95% cases. The objective of the present study is to see most common micro organism in bile culture and their antibiotic susceptibility in eastern Indian population. Methods : The present institution based prospective observational study was conducted in the Dept of General Surgery, Burdwan Medical College and Hospital, Burdwan, West Bengal, India between April 2021 to September 2022. Total 75 patients with chronic calculous cholecystitis underwent cholecystectomy were included in the study after applying inclusion criteria and taking informed consent. Statistical data were analysed by using Microsoft Excel and SPSS V.21 software. Results : Mean age of 46.05 ±12.15 years. There was a female predominance with 49 females (65.3%) and 26 (34.7%) male out of 75 patients. The mean levels of height, weight and BMI among the study participants were 159.35 ±5.70 cm, 70.35 ±6.80 kg and 27.78 ±3.46 kg/m2 respectively. most patients (60%; 45 out of 75) did not have any co- morbidity while 18 (24%) patients had diabetes mellitus, 9 (12%) patients had hypertension, and 3 (4%) had hypothyroidism. Most common clinical symptom among study participants was pain in upper abdomen (64%) followed by dyspepsia (50.7%), nausea and vomiting (16%). The most common indication of chronic calculus cholecystitis was sedentary lifestyle (45.3%) followed by hyperlipidemia (40%), high fat diet (34.7%) and oral contraceptive pills (24%). USG of abdomen confirmed the incidence of cholecystitis in all 75 cases. Out of 75 cases 19 (25.3%) underwent laparoscopic cholecystectomy and 56 (74.7%) underwent open cholecystectomy. Out of 75 cases cholesterol stones (65.3%) were the most common type of stones found among study participants followed by pigmented stones (26.7%) and missed type of stones (8%). Conclusion : Bacterial growth in chronic calculus cholecystitis is not very common however the identification of microorganism after cholecystectomy can be used as a useful tool in the management of these patients and consequently reduces the morbidity and mortality

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