Abstract

Left ventricular function is the best individual predictor of mortality after acute myocardial Infarction. After acute myocardial infarction (AMI), a patient’s prognosis is closely related to the extent of irreversibly damaged myocardium. The cardiac Troponin T (cTnT) has been found to have excellent sensitivity and specificity and is superior to creatine kinase–MB (CK-MB) as indicator of myocardial necrosis. The purpose of the study was to compare the QRS score with left ventricular ejection fraction, relate the score to clinical and biochemical estimates of LVEF. Material and Methods: The study was carried out in a study group of consecutive 88 patients admitted in ICCU. Serum troponin T concentration was measured between 12 - 48 hours after the onset of chest pain. Standard 12 lead electrocardiograms were recorded at a 25 mm paper speed for the patients who met the preceding entry criteria had a QRS score calculated from the discharge electrocardiogram on the basis of Q and R wave duration and R to Q and R to S amplitude ratios. Results: Mean age of the patients in present study was 52±12. Most of the patients in our study were in age group 41-60yrs (82.5%). 67% of patients had AWMI and 33% patients had IWMI, 60% patients had dyslipidaemia. There was a strong negative correlation between cTnT level and Echocardiographic LVEF. The relationships between QRS Score and the indices of LV function obtained by Echocardiography performed at the time of ICCU discharge, QRS Score was inversely correlated with LVEF. There was a negative correlation between QRS Score and LVEF. Conclusion: A strong negative correlation exists between the serum troponin T concentration and left ventricular ejection fraction following the occurrence of a first acute myocardial infarction. Therefore, using serum troponin T concentration can be an effective way to evaluate the LVEF in patients who have experienced their first myocardial infarction.

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