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Journal of Cardiovascular Disease Research

2021, Vol: 8, Issue: 8
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    Remogliflozin: Add-on Therapy in Indian Uncontrolled Type 2 Diabetes Mellitus (T2DM) Patients


    Deepak Jaiswani , Vinod Kumar Singh2 , Pinki Lohan , Priya Singh
    JCDR. 2023: 819-824

    Abstract

    Material and Methods: This prospective and interventional study was carried out on eighty-one T2DM patients in Teerthanker Mahaveer Medical College & Research Center, Moradabad over a period of 18 months. Results: Out of 81 study subjects, 61.7% were male while 38.3% subjects were female. Majority of study subjects (46.9%) were in the age group 51-60 years. There was a decrease in the mean diastolic blood pressure (82.91 vs 80.86), weight (68.57kg vs 67.92kg), fasting blood sugar (177.68 mg/dl vs 162.83mg/dl) and 2 hour post prandial sugar (252.64 mg/dl vs 229.81mg/dl) from the baseline values. This difference was statistically significant with p-value <0.05. Conclusion: Add-on therapy with RE in T2DM patients on oral hypoglycemics demonstrates significant reduction in diastolic BP, body weight, FBS & PPBS within one month of therapy without significant change in systolic BP. This drug is not only well tolerated by T2DM patients but also has a very low risk of serious adverse events rarely requiring dose modification in T2DM patients with high-risk cardiovascular disease or renal impairment

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    Volume 14 Issue 5

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