Journal of Cardiovascular Disease Research
ROLE OF AMINOPHYLLINE IN PREVENTING RENAL DYSFUNCTION IN NEONATES WITH PERINATAL ASPHYXIA
Dr. Sonal Mehta , Dr. Manmeet Kaur Sodhi , Dr. Vipul , Dr. Navjot Kaur , Dr. Kirandeep kaur
JCDR. 2023: 1530-1537
Abstract
Background: Perinatal asphyxia is a common neonatal problem that contributes significantly to neonatal morbidity and mortality. Perinatal asphyxia is perceived to be the primary cause of transient renal dysfunction or acute renal failure. Adenosine plays an important role in tubuloglomerular feedback. Aminophylline is an adenosine receptor inhibitor, thus promotes renal perfusion and decreases solute load. Objectives: To study the role of aminophylline in preventing renal dysfunction in neonates with perinatal asphyxia
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