Journal of Cardiovascular Disease Research
Role of Asp299Gly single nucleotide polymorphism of TLR4 gene in susceptibility of idiopathic dilated cardiomyopathy
PARAMITA DEY, PROF NIRUPAMA DEVI, KARUNAKARA PADHY, SARADA ASIS DASH, SASWATI SATPATHY, RASHMI PRABHA SAHU, PRASANT PUROHIT, DIPTIMAYEE JENA
JCDR. 2024: 4151 -4164
Abstract
Introduction: cardiovascular diseases remain one of the major reasons of universal mortality and accounts for 31% of deaths alone in India. Cardiomyopathy is one such cardiovascular anarchy that is linked with heterogenous aetiologies leading to ventricular hypertrophy and myocardial dysfunction. Between 2008-2015, owing to cardiomyopathies there has been significant increase in evidences of hospitalisation for heart failure, mechanical circulatory supports, defibrillators implantations and 51% of all heart transplants [Lannou Set al, 2020].
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