Abstract

Acute pancreatitis is a disorder characterized by an immediate inflammation of the pancreas. Patients with severe acute upper abdomen discomfort should be suspected of having acute pancreatitis; nevertheless, the diagnosis needs either biochemical or radiologic proof. Aims and objectives: The goal of this research is to establish the function of a biochemical marker in predicting acute pancreatitis. Methods: This is retrospective research that was place in the Department of Biochemistry and Surgery at SRM Medical college, Kalahandi from May to November, 2023. Age, gender, serum amylase levels, and lipase amylase lipase ratio were among the information gathered from medical records. Results: Of the 90 patients, 73.3% were men (n=66) and 26.7% were females (n=24). The patients in this research had a mean age and SD of 38.5±2.2.5 years. The mean and standard deviation for Amylase, Lipase, and Amylase Lipase Ratio were 870.3±754.23, 235.8±124.5, and 3.87±2.45. The sensitivity and specificity of amylase and lipase at three times the normal limit was 83.33% and 84.88%, respectively. Positive predictive value: 85.23%; negative predictive value: 82.95%. Accuracy: 84.09%. Conclusion: In patients with abdominal discomfort consistent with acute pancreatitis, the ACG practice recommendations regard a lipase and/or amylase rise larger than three times the ULN as diagnostic. Lipase is somewhat more specific to acute pancreatitis than amylase. It increases sooner and remains higher than serum amylase in AP patients. Serum lipase outperformed serum amylase in diagnostic accuracy.

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