Abstract

Background: Although the pathophysiology and clinical significance of thoracic aortic calcification are yet unknown, it is linked to atherosclerotic risk factors. The current study set out to determine whether patients with stable angina pectoris who also had calcification of the thoracic aorta had a higher chance of cardiovascular events and mortality. Methods and Results: 152 individuals (98 men, 54 women; ages 35 to 80 years) with stable angina pectoris were included in a prospective cohort that had chest computed tomography to screen for aortic calcification. Over 1-year follow-up, we documented the incidence of cardiovascular events and deaths. There were 106 patients (70% of patients; 83 men and 23 women) with proven aortic calcification. Aortic valve calcification (28% against 11%; p<0.001), mitral annulus calcification (29% versus 4%; p<0.001), and coronary calcification were observed to be significantly correlated with the occurrence of aortic calcification in individuals. Cardiovascular events and mortality is noted significantly to be associated with thoracic aortic calcification (p<0.001). Conclusions: Age-related calcification of the thoracic aorta is linked to valvular and coronary calcification. Cardiovascular illness and a higher risk of death are linked to thoracic aortic calcification.

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