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Journal of Cardiovascular Disease Research

2021, Vol: 8, Issue: 8
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    ROLE OF DIFFUSION WEIGHTED MAGNETIC RESONANCE IMAGING IN EVALUATION OF CHOLESTEATOMA


    Dr Shreelatha A, Dr Anand Madappanavar, Dr Vindya Krishna, Dr Vasanth kumar L
    JCDR. 2024: 304-312

    Abstract

    Objective To evaluate the diagnostic performance of Diffusion-Weighted Magnetic Resonance Imaging (DWI-MRI) in the detection of cholesteatoma and assess its potential to replace second-look surgery. Methods This prospective observational study recruited 65 patients with suspected cholesteatoma and compared DWI-MRI findings with histopathological examination (considered the gold standard). HRCT temporal bone scans were also performed for comparison. Results • DWI-MRI demonstrated high sensitivity (94.23%) and specificity (100%) for cholesteatoma detection. • DWI-MRI outperformed HRCT in both primary (93.8% vs. 87.5%) and recurrent/residual cholesteatoma cases (80% vs. 25.0%). • Mean ADC values were significantly lower in cholesteatoma compared to granulation tissue and inflammatory tissue.

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    Volume 15 Issue 4

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