Abstract

Coronary Artery Disease (CAD) occurs at a younger age in Indians. Atherosclerosis is the most common pathological process that leads to cardiovascular diseases. The Framingham risk score (FRS), known as an important instrument in predicting coronary artery disease in patients with traditional risk factors, such as dyslipidaemia, hypertension, diabetes mellitus (DM), and smoking, seems to have underestimated the coronary artery disease risk in individuals with high homocysteine plasmatic levels. Inborn errors of metabolism arising from a deficiency of Homocysteine (Hcy)-metabolizing enzymes result in extremely high Hcy concentrations and are associated with atherosclerosis and premature thrombosis. In this study we made an attempt to find out the role of homocysteine as a nontraditional risk factor in young adults with acute myocardial infarction

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