Abstract

The analytical errors may be random or systematic which is devoted by basically inaccuracy and imprecision. These parameters are represented by coefficient of variation (CV) and Bias. The exact number of errors done by the laboratory in the analytical phase cannot be assessed by running internal and external QCs, but can be quantified by sigma metrics. Sigma measures low far a given process deviates from perfection. Six sigma is one of the popular quality management system tools employed for process improvement which combines bias, precision and total allowable error sigma value <3 indicates poor performance, where as >3 indicates good performance.

Description