Journal of Cardiovascular Disease Research
Serum BNP level's importance in the tertiary hospital's heart failure study with preserved ejection fraction
Dr. Purnima B Potharlanka, Dr. Rajesh Kumar Palaparthi, Dr. Lalitha Palaparthi, Dr. Surekha Kadamati
JCDR. 2024: 1053-1057
Abstract
Background and Objective: In order to investigate the significance of serum B type Natriuretic peptide levels in individuals who exhibit acute left heart failure while maintaining their ejection fraction Method: This study included 40 patients with a diagnosis of diastolic dysfunction who presented to emergency department. BNP values, a thorough 2D Echo, and standard blood samples were obtained. The chi-square test, percentage, and standard error of proportion were used in the statistical study. Result: In the current study, 40 HFPEF patients were included, with a mean age group of 64.86 years. The majority of the patients (65%) were female, and their mean BMI was 25.24 kg/m2. They were overweight, with concomitant comorbidities including diabetes mellitus (64%) and hypertension (70%). The majority of the patients in the current study had higher BNP levels, which were significantly correlated with all the criteria, including age, sex, comorbidities, LA size (p-0.001), Diastolic Dysfunction type (p-0.033), and NYHA grade. Conclusion: Monitoring the preclinical course of diastolic illness and preventing hospitalisation for heart failure should be the main priorities. Therefore, research needs to be done to determine whether patients would benefit from more monitoring and stricter management of their risk factors.
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