Abstract

The condition known as diabetes mellitus is the metabolic disease that is most prevalent among people all over the world. It is well-established that diabetes mellitus is linked to both lipid problems and the development of cardiovascular diseases. The patients with diabetes mellitus who visit the outpatient department of medicine at HSK Hospital and Research Centre are going to participate in this study so that researchers can evaluate how their lipaemic levels have changed. Researchers looked at the levels of total cholesterol (TC), triglycerides (TG), LDL cholesterol (LDL-C), and HDL cholesterol (HDL-C) in the serum of people with diabetes. This is a case control study in which the cases consisted of 76 diabetic patients and the controls consisted of 50 individuals of the same age range and gender. All of the samples were taken from people who had abstained from food for at least a day and a half prior to having their blood drawn. Manual analysis using a spectrophotometer and liquid chemistry were employed in order to arrive at the values for the parameters. In both IDDM and NIDDM, the levels of triglycerides, total cholesterol, and LDL cholesterol were all greater in patients' bodies compared to those of healthy controls. The HDL-C levels of patients with NIDDM who were taking sulfonylureas or biguanides were dramatically decreased, whereas the HDL-C levels of IDDM patients who were taking insulin did not significantly change. In patients with NIDDM, there was a strong association between FBS and total cholesterol, total fat, LDL-C and HDL-C. In participants with IDDM, there was a substantial association between TC, TG, and LDL-C.

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