Abstract

Infection with the dengue virus has become a major public health concern in the last few years because the magnitude of the symptoms has increased dramatically.. There are many different signs of hepatic involvement by dengue, ranging from a hepatic enlargement to deranged liver enzymes and fulminant hepatic failure. Material and Methods: A prospective study was done between April 2022 to March 2023, at the department of paediatrics,Government General Hospital and Kurnool Medical College, Kurnool, Andhra Pradesh.This was a prospective Cohort Study.Around 125 children who tested positive for dengue serology and admitted were recruited in the study. Children who tested positive for Dengue Serology were thoroughly examined clinically for fever and hepatomegaly. Results:All of the subjects had high grade fever. Fever was most documented in children between 5 to 8 years old.. .The fever was high grade with headache and retrooebital pain.Hepatomegaly was the most common clinical sign documented. The presence of thrombocytopenia was noted in 88% of cases. Serum total bilirubin levels were raised in 12percent of subjects with severe dengue illness. Conclusion: Dengue fever epidemics have been linked to uptrend in hepatic involvement in developing countries like India.. Since hepatic impairment is transient and reversible in dengue, early diagnosis and treatment aids in preventing potentially fatal outcome.

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