Journal of Cardiovascular Disease Research
Study of Association of BMI with glycemic control in type 2 diabetes mellitus patients
Hemant Bhaskar Makone, Bhagyashri Ahirrao, Geeta Rohit Hegde, Shital Abhijeet Hiray
JCDR. 2023: 2246-2253
Abstract
To elucidate the association between BMI and glycemic control, quantified via glycated hemoglobin (HbA1c), in a sample of 200 individuals diagnosed with T2DM. Methods: This cross-sectional analysis engaged 200 T2DM patients from a tertiary healthcare facility. Comprehensive data encompassing demographic attributes, medical background, and pertinent lab results, primarily HbA1c, were systematically recorded. For the purpose of this study, participants were stratified based on their BMI classifications: underweight, normal weight, overweight, and obese. The correlation between these BMI groupings and their corresponding HbA1c readings was statistically scrutinized. Results: Among the 200 subjects, a distinct distribution was noted: 32.5% were classified as overweight, 32.5% as obese (considering all three obesity categories combined), 25% had a normal BMI, and 10% were underweight. A pronounced association was discerned whereby individuals with a higher BMI displayed elevated HbA1c levels, signifying suboptimal glycemic control. The obese subgroup (specifically the Obesity III category) recorded the peak average HbA1c of 7.9%, in contrast to the lowest average of 5.7% noted in the underweight cluster. Conclusion: The findings confirm a significant correlation between BMI and glycemic outcomes in T2DM patients within our sample. Those with elevated BMI, especially the obese cohort, manifested compromised glycemic control. This underscores the potential merits of weight-centric interventions in facilitating optimal glycemic regulation for T2DM patients.
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