Abstract

Introduction and Aim: Asthma is a variable condition which gives load to patients, their families and community. Diabetes involved multiple factors and also cardiovascular risk factors are signs of pre-diabetic. Asthma is directly proportional to coronary artery disease. Materials and methods: Blood sample for HbA1c and HCY was collected in EDTA vial. HbA1c determination was based on turbidimetric inhibition immunoassay (TINIA) on Roche cobas c311 auto-analyzer kit. HCY was measured by ELISA method on ELISA Reader (Tulip) by using Alpha diagnostic international kit. The subjects enrolled were 165 asthmatic patients and 165 healthy controls. Results and conclusion: When comparing means of different biochemical parameters between controls and cases with student’s t-test, HbA1c, Cholesterol, HDL, TG, LDL and HCY showed a highly significant (p<0.0001) difference. Adult with asthma, particularly those using multiple medications may be at increased risk of diabetes and CAD.

Description