Abstract

Diabetes mellitus is a metabolic disorder of multiple aetiology, characterised by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. Objectives: To evaluate the status of distal symmetrical polyneuropathy and painful neuropathy using MNSI scoring system and DN4 questionnaire respectively and cardiac autonomic neuropathy using Bellavere’s scoring system in patients of this geographical area. Materials and Methods: This cross sectional study was conducted among admitted patients presenting to Department of Medicine, Government medical College, GGH, Srikakulam. Results: Most of the subjects belonged to 6-10 years duration. Based on BMI 13 were underweight,60 were normal, 32 were overweight, 61 were Obese I, 4 were Obese II. 57.05 % of the subjects had abnormal BMI. 36 subjects had normal waist hip ratio. Based on HbA1c levels, most subjects (112) were in range between 6.5-9. Gender vs Neuropathy assessment showed, 16 males and 46 females had neuropathy with P value 0.106, which is statistically not significant, other studies showed neuropathy is more common in males. Age of subject (yrs.) vs neuropathy (P value 0.52) showed non significance,. In my study most of the subjects were diagnosed incidentally and the duration of diabetes based on history may not be the exact duration from which the study subjects were actually suffering from diabetes, hence the duration of diabetes vs neuropathy (p value 0.452) showed no significance. Comparison of Neuropathy vs BMI (p value 0.576) had no statistical significance. Waist hip ratio vs Neuropathy (p value 0.406) also was not significant. Neuropathy was more with subjects with higher values of Fasting blood glucose (Pvalue0.002) which is statistically significant. Conclusion: Neuropathy was more in subjects with higher of HbA1c. (p value 0.001) which is statistically significant

Description