Abstract

Tuberculous pleural effusion is traditionally linked to elevated adenosine deaminase (ADA) activity in the pleural fluid. Nonetheless, elevated activity can also transpire in several other ailments, which could potentially compromise the diagnostic efficacy of ADA assessments and reduce their specificity in tuberculosis (TB) diagnosis. The cellular immune response in the pleural cavity, and specifically the activation of T lymphocytes, is reflected in the presence of ADA in pleural fluids. Specific types of leukocytes are generally linked to different disease entities. The current study's goal is to assess how well the lymphocyte/neutrophil ratio and ADA activity work together to diagnose tuberculous pleural effusion.

Description