Journal of Cardiovascular Disease Research
Study of echocardiographic assessment of Left ventricular diastolic dysfunction in normotensive Type 2 Diabetes mellitus patients
Mohit Chaudhari, Abhijit Mulay, Digvijay Shinde
JCDR. 2023: 2406-2415
Abstract
Diabetes mellitus is one of the most common diseases in the world and is acquiring epidemic proportions. Acute, life-threatening consequences of uncontrolled diabetes are hyperglycemia with ketoacidosis or the nonketotic hyperosmolar syndrome. Diabetes mellitus also can affect cardiac structure and function in the absence of changes in blood pressure and coronary artery disease, a condition called diabetic cardiomyopathy. Methodology- The study was conducted at Department of Medicine of Pravara Rural Hospital, Loni from September 2014 to August 2016. 50 patients who were newly detected as well as known case of diabetes mellitus type 2 were included in the study. All the subjects underwent resting transthoracic 2-dimensional echocardiography and Doppler imaging, to assess left ventricular diastolic function. Data was analyzed using SPSS-16 for windows. Result-Out of total study population, diastolic dysfunction was present in 27 (54%) cases. Out of 50 cases 24 (48%) had grade I, 3 cases (6%) had grade II diastolic dysfunction and 23 cases (46%) had no diastolic dysfunction. Presence of diastolic dysfunction in population with age more than 45 years was found to statistically significant in male population as compared to female population. E/A ratio was found to be very significantly low in diabetic patients with diastolic dysfunction as compared to diabetic patients without diastolic dysfunction. Conclusion- Diastolic dysfunction in type 2 DM is significantly dependent on the duration of diabetes mellitus. As the duration of diabetes increases presence of diastolic dysfunction increases in asymptomatic type 2 DM population.
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