Abstract

Aim and objectives: 1) To evaluate the effects of haemodynamic changes during Laryngoscopy and tracheal intubation using inj. dexmedetomidine and inj. clonidine. 2) To compare haemodynamic changes during Laryngoscopy and tracheal intubation using inj.dexmedetomidine and inj.clonidine. 3) To compare the side effects. Materials & Methods After approval of the institutional ethical committee, this prospective observational study was conducted on 60 patients of ASA Grade I & II, undergoing elective surgeries under general anesthesia. Group D: injection Dexmedetomidine o.5mcg/kg diluted to 20ml with normal saline were given over 10 minutes. Group C: injection. Clonidine 1mcg/kg diluted to 20ml with normal saline were given over 10 minutes. All patient received Injection Pentazocine 0.3mg/kg and were pre-oxygenated for 3minute Anaesthesia was induced with thiopantone sodium (5mg/kg intravenous) till loss of eyelashreflex over 30 second and mask ventilation was confirmed. Injection succhinylcholine 1.5mg/kg was given to facilitate laryngoscopy and intubation. anaesthesia was maintained with oxygen nitrous oxide ,halothane with intermittent use of injection Atracurium and controlled ventilation. At the end of surgery the neuromuscular blockade was antagonized with injection Glycopyrolate (.01mg/kg)Intavenou .and injection Neostigmine(.05mg/kg)i.v. and patient were extubated.

Description