Journal of Cardiovascular Disease Research
Study of HER2/neu Overexpression in Colorectal Carcinoma at a Tertiary Care Centre in Rajasthan, India
Dr. Shipra Singh, Dr. Santosh Kumar Singh, Dr. Saroj Ola, Dr. Nikita Manoj
JCDR. 2024: 3351-3354
Abstract
Colorectal cancer remains one of the major leading causes of death worldwide. The therapeutic implications of Human Epidermal Growth Factor (HER2/neu) in certain cancers like breast cancer and gastric cancer has already established. The prognostic significance of molecular marker HER2/neu in colorectal cancer is unclear and studies have shown wide range of positivity, 0%-83%. This study was undertaken to study overexpression of HER2/neu in colorectal cancer, hence opening doors to new modalities of treatment.
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