Abstract

Aim and Objectives: The purpose of this study is to determine the prevalence of metabolic anomalies associated with neonatal convulsions. It was chosen to study the relationship between the early clinical symptoms and neonatal seizures. Methods: Hospital-based, prospective study of newborns admitted to a department of paediatric DR VRK, Women’s Medical College, Aziz Nagar, Hyderabad, Telangana, India, within the first 28 days of life. 50 infants participated in the trial, which ran from March 2022 to February 2023. The most common type of infant metabolic abnormalities was observed in this investigation. Results: From day 1 to day 17, the median age at first seizure start was 3.26 (95% CI 2.40 to 2.72). Thirty-three of the seizures (33%) in our study began during the first 24 hours, while others began between 24 and 72 hours (days 1-3), 4 to 7 days (days 4-7), and beyond 7 days (9%). Nearly nine in ten cases of convulsions occur on day one. 14 (56%) premature infants had mild seizures, 7 (28%) of which were tonic and 4 (16%) were clonic. Conclusion: Newborns frequently experience convulsions. The numerous causes of newborn seizures affect the course of the condition and its long-term neurological prognosis, mortality, and morbidity

Description

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