Abstract

Background: Chronic respiratory disease is a collection of conditions that affect the lungs and airways primarily. It is linked to considerable morbidity and mortality. Because India has the biggest TB burden of any country on the planet, it is quite likely that it also has a significant burden of COPD that is related with TB. Present study was aimed to study prevalence of tuberculosis in diagnosed cases of chronic obstructive pulmonary disease. Material and Methods: Present study was single-center, prospective, observational study, conducted in adults more than 18 years age, who had a definite history of pulmonary or extra pulmonary tuberculosis, had received complete anti-tuberculous therapy course & with a history of COPD diagnosis and presenting with chronic dyspnoea. Results: Among 119 patients, majority were males (73.1%). Mean age of the study population was 58.59 ± 12.89 years. Majority of the study Population had GOLD stage 2 of COPD (53.8%), while 21% had Stage 3 and 10.1% had stage 4 COPD. Prevalence of TB in COPD patients in the present study was found to be 28.6%. Amongst those with a history of TB, Patients with history of extra pulmonary TB had less severe stage of COPD. Majority of those with history of Pulmonary TB, presented with Stage 3 (12.6%) and Stage 4 (7.6%) of COPD. Spirometry observations of FEV1, FVC and FEF25-75 were significantly lower in Patients of COPD with previous history of Tuberculosis. There is a statistically significant association between history of TB and Severity of COPD. Conclusion: Prevalence of Tuberculosis in patients of COPD was 28.6%. Spirometry observations of FEV1, FVC and FEF25-75 were significantly lower in Patients of COPD with previous history of Tuberculosis.

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