Abstract

COVID-19 is a global pandemic caused by [severe acute respiratory syndrome-corona virus] SARS-CoV-2 which belongs to genera beta corona virus. In the pathogenesis of the present pandemic many inflammatory markers are being rised and are causing cellular damage. Objectives of present study includes [1] study serum ferritin levels in type 2 diabetes mellitus patients who are confirmed as covid positive cases by RT-PCR technique and[2] To compare serum ferritin in covid cases without any co-morbidities. Methods: - Present study is a case control study done at department of Biochemistry at state covid clinical laboratory, Government general hospital, Kurnool, Andhra Pradesh for about 4 months from April2020 to July 2020. It includes 50 covid positive cases who are known diabetic and 50 were controls who are also tested covid positive but without any co morbidities. Results:-Data is entered in excel spreadsheet and statistically analyzed using spss software. Mean with serum Ferritin in cases is 573.13±94.79, P value-˂0.0001 and controls are 268.50±40.48, P value- <0.0001. Conclusion:- A statistical significant results shows that high serum ferritin levels in covid positive diabetes mellitus cases is attributed to cellular damage caused by hyperglycemia and in turn serum ferritin causing hyperinsulinemia and hyperglycemia

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