Abstract

Congenital Hypothyroidism is one of most common preventable cause of mental retardation in children and hyperbilirubinemia is the most common cause of readmission of newborn after discharged from hospital. Objective: To determine the association between serum bilirubin, TSH level and birth weight in full term neonates. Material and Methods: This Observational - Cross sectional study was conducted among Term Newborns delivered in the Department of Pediatrics in Vydehi Institute of Medical Sciences and Research Centre, Bangalore.Duration of study was March 2021 to August 2022. Results: Mean concentration of bilirubin levels, TSH levels in group 1 was 13.97mg/dl and 5.23mIU/ml respectively and in group 2 was 16.41mg/dl and 7.46 mIU/ml respectively. Mean TSH and bilirubin level of newborns <2.5kg was 7.65mIU/ml and 17.21mg/dl and in newborns >2.5kgwas6.55 mIU/ml and 15.29mg/dl respectively. Conclusion: simultaneous measurement of serum bilirubin levels and TSH levels can be useful for screening congenital hypothyroidism. Neonates with low birth weight (<2.5kgs) did not show statistically significant association with serum TSH level whereas it shows statistically significant association with serum bilirubin level

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