Abstract

Background: Thrombocytopenia is defined as platelet count < 1.5 lakhs/ml. Thrombocytopenia can be classified into. 1. Pregnancy specific: Gestational thrombocytopenia (70-80%) Severe pre-eclampsia (15-20%), AFLP (<1%) 2. Non Pregnancy specific: ITP (1-4%), rarer causes like TTP (0.5%)/HUS, SLE, APLA syndrome (0.5%), DIC (5%) viral infections, malaria, drug induced, bone marrow disorders. Subjects and Methodology: This is an observational study conducted at Gandhi hospital from 2019 to2022 during which 200 antenatal women with Thrombocytopenia (<1.5 lh/ml) were enrolled at first visit, irrespective of gestational age and evaluated. Results: Out of 200 cases, 80 cases (44%) had PIH which is considered as the most common etiology followed by gestational thrombocytopenia. 60% (120) of cases were of age group of 21-25 years. 34% (68) of the cases received blood transfusions. 48% (96) of the cases were Primigravida, 83% (96) of cases delivered at >37 weeks gestation. 52% (104) of cases had moderate thrombocytopenia, 24%(48) had severe thrombocytopenia. 22% (44) of cases had gestational Diabetes Mellitus, 21% (42) of the cases had anemia and 11.5% (23) had hypothyroidism. About 57% (114) of cases had a vaginal delivery. Out of 200 cases, no maternal deaths were reported. Complications like abruption in 6% (12), PPH in 4%, (8) Blood transfusions in 34% (68). Perinatal complications - 30% (60) of cases had babies with Birth weight <2.5 kg. 93% (186) of cases had babies with APGAR >7 at 5 minutes. 4.5% (9) of cases had babies with IUGR, 3.5% (7) of the babies had neonatal thrombocytopenia.

Description