Abstract

Acne vulgaris is a common chronic inflammatory disease of the skin. It is found in about 80% of young adults and adolescents. It causes discomfort, emotional stress, disfigurement and even permanent scarring to the skin. It may also cause anxiety and embarrassment in patients and may diminish the patient’s physiological and social wellbeing. Mild acne is often treated with topical retinoids, or a variety of diverse treatments such as azelaic acid, salicylic acid and benzoyl peroxide Material & methods: Eighty six patients with mild to moderate facial acne were selected for this study after informed consent. Group A received topical adapalene and 1% clindamycin daily along with 40% pyruvic acid peel once in two weeks for total period of 3 months. Group B received topical adapalene with 1% clindamycin daily without peel for a period of 3 months. Results: Results were analyzed by Chi-square test. In Group A 36 patients and in group B 38 patients completed the treatment. Four patients in group B developed local irritation to adapalene. Among 36 patients in group A, 80% showed complete clearance in 12 weeks. Conclusions: In this study we conclude that, topical adapalene, clindamycin with pyruvic acid peel combination showed an early reduction of acne lesions when compared topical adapalene and clindamycin alone

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